Early Depictions of the Crucifixion

Early Crucifixion Depictions showed nails through the center of the palm, not the wrist.

The Crucifixion, Pieter Coecke van Aalst, c. 1525-35

 

Rembrandt's Crucifixion 1631
 

Christ Crucified - Diego Velázquez (17th century)

Sources

1. http://www.nationalgallery.org.uk/paintings/circle-of-pieter-coecke-van-aalst-the-crucifixion-central-panel

2. http://www.everypainterpaintshimself.com/article/rembrandts_crucifixion_1631

3. http://arquitecturaycristianismo.com/2013/02/17/el-cristo-crucificado-de-velazquez/